We study the pattern and consequence of genome instability evolution by combining real-time evolutionary experiment and in silico genomic analysis. On one hand, we directly introduce various genome instability structure to the cell and to monitor evolution in action; on the other hand, we also dig into the genomic data generated by both basic and clinical research to retrospectively reconstruct the path of genome instability evolution and shed light on its clinical implications.
Our bench for wetlab experiments. Our servers for bioinformatics computation.